CELLBANKER’s Scientific Annual Report (2021)

ZENOAQ has issued publications on research of cell cryopreserved regularly. Here is the summary for the publication of 2021.

・The total number of citations in 2021 was 178 and reached a record-high.

・The number of the cited scientific articles was 125 (contain preprints).

・It was published in many prestigious scientific journals in the year 2021, too.

(e.g. Nature, Cell Stem Cell, Nature Protocols, Nature Communications, Proc Natl Acad Sci USA, The EMBO Journal, Cell Reports, Science Advances, Scientific Reports, STAR Protocols, etc.)

Preserved Samples /CELLBANKER type	Articles
cGMP manufactured MSK-DA01 cells /STEM-CELLBANKER	Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01. Piao J, et al., Center for Stem Cell Biology, Memorial Sloan Kettering Cancer Center, New York, *Cell Stem Cell, 2021, 28(2):217-229.e7. Parkinson’s Disease Preclinical Study*
Naïve human PSC derived trophectoderm, Naïve PSC-derived cytotrophoblast /STEM-CELLBANKER	Capturing human trophoblast development with naive pluripotent stem cells in vitro. Io S, et al., Department of Life Science Frontiers, CiRA, Kyoto University, *Cell Stem Cell, 2021, 28(6):1023-1039.e13. Organoid Study*
Tumor-derived spheroids from uterine endometrial and ovarian malignant tissues /STEM-CELLBANKER DMSO Free	Establishment of in vitro 3D spheroid cell cultivation from human gynecologic cancer tissues. Ueda H, et al., Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, *STAR Protocols, 2021, 2(1):100354. Spheroids*
Tumor samples for preimplantation /STEM-CELLBANKER DMSO Free	Characterization of the large-scale Japanese patient-derived xenograft (J-PDX) library. Yagishita S, et al., Division of Molecular Pharmacology, National Cancer Center Research Institute, *Cancer Science, 2021, 112(6):2454-2466. PDX Model Study*
Human PBMC /CELLBANKER 1	mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants. Wang Z, et al., Laboratory of Molecular Immunology, The Rockefeller University, New York, *Nature, 2021, 592: 616–622. COVID-19 Study*
iPSC derived foregut cells /CELLBANKER 1	High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell–Derived Organoids. Shinozawa T, et al., Developmental Biology and Center for Stem Cell and Organoid Medicine (CuSTOM), Cincinnati Children’s Hospital Medical Center, *Gastroenterology, 2021, 160(3): 831-846.e10. Organoid Study*
CAR-T cells /CELLBANKER 2	Peripheral leukemia burden at time of apheresis negatively affects the clinical efficacy of CART19 in refractory or relapsed B-ALL. Deng B, et al., Cytology Laboratory, Beijing Boren Hospital, Beijing, *Molecular Therapy – Methods & Clinical Development, 2021, 23: 633-643. CAR-T Cell Study*
Liver tissues /CELLBANKER 2	Regional Differences in Human Biliary Tissues and Corresponding in Vitro Derived Organoids. Rimland CA, et al., Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, *Hepatology, 2021, 73(1):247-267. Organoid Study*